Which condition is described as a degenerative kidney disease causing nephritic syndrome without inflammation?

• A. Nephritis
• B. Pyelonephritis
• C. Nephrosis
• D. Nephrotic syndrome

Answer: (C)

Nephrosis is the best fit because it describes a degenerative, non-inflammatory disease of the kidney. This noninflammatory process affects the glomeruli and typically leads to the nephrotic syndrome pattern (heavy proteinuria, hypoalbuminemia, edema, and often high cholesterol). In contrast, nephritis is inflammatory and causes nephritic syndrome with features like hematuria and red blood cell casts. Pyelonephritis is an infection with inflammatory signs, and nephrotic syndrome refers to the syndrome itself rather than a disease process. So, the degenerative, non-inflammatory nature points to nephrosis as the correct answer.